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KAUST finds a compound that may help develop treatments for muscle diseases

KAUST finds a compound that may help develop treatments for muscle diseases

KAUST finds a compound that may help develop treatments for muscle diseases

King Abdullah University of Science and Technology has revealed new research that may lead to new treatments for muscular degenerative diseases.

The university stated that biochemist Dr. Brenda Janice Sanchez succeeded with her colleagues at King Abdullah University of Science and Technology (KAUST) and McGill University in Canada in identifying an important protein compound that supports the stability of messenger RNA during the formation of muscle fibers.

And she showed that RNA is a fragile molecule, and it is similar to DNA, but differs from it in that it is much smaller, and it works as a mediator or messenger that carries the genetic code copied from the DNA to the protein factories in the cell, where the code is translated. To form the various little ingredients that make us who we are.

She added that the compound that was reached consists of two proteins, namely: the human antigen R “HuR” and the binding protein Y-Box 1 “YB1”, stressing the need to discover the exact roles of each protein separately in the process of RNA stability, because this may help scientists Controls the amount and types of proteins made in the muscles as well as in other tissues at any given time.

“Learning how to control RNA turnover during muscle fiber formation could have huge ramifications for developing new therapies that prevent muscle-related diseases,” said Brenda Sanchez.

KAUST finds a compound that may help develop treatments for muscle diseases

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